HISTAMINE
The Neurotransmitter
Histamine is an endogenous substance that puts the body on alert in the event of infections or allergic reactions. In the case of intolerance caused by the body's own histamine or histamine ingested through food, this is referred to as histamine intolerance. The symptoms are non-specific and often do not allow for a clear diagnosis. Since the causes are varied and there are no clear criteria, there is no reliable laboratory test.
HISTAMINE
From food
Histamine is also found in a lot of foods. Processed, matured, preserved and fermented foods in particular contain large amounts. Histamine is also found
in fresh foods*.
It is broken down in the small intestine by the body's own enzyme diamine oxidase (DAO) .
*For a more detailed catalogue, see our food list.
INTOLERANCE
Intolerance
Histamine intolerance refers to the imbalance between histamine presence and its degradation.
When the body does not produce enough DAO to break down the histamine from food, it enters the bloodstream and causes all kinds of symptoms.
However, foods do not necessarily have to contain histamine to cause symptoms.
Histamine liberators (e.g. strawberries, seafood, nuts) cause the release of the body's own histamine. DAO blockers (e.g. alcohol and caffeinated drinks) prevent the production of DAO in the small intestine. And other amines similar to histamine can also cause symptoms.
SYMPTOMS
A long list
The list of symptoms that can manifest as a result of histamine intolerance is very long. These symptoms can occur in different combinations in different people, which makes diagnosis difficult and is why HIT is often confused with allergies .
The excess histamine stimulates histamine receptors and the body begins to react:
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Diarrhea
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Abdominal pain, cramps
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Digestive problems
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Heartburn
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Flatulence
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Constipation
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Nausea
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Vomit
HISTAMINE INTOLERANCE
In everyday life
Nowadays allergens are already listed on restaurant menus, but histamine awareness is not yet well established in society.
In order to remain free of symptoms, those affected must not only give up comfort and
pleasure, but also many foods that would otherwise constitute a healthy and varied diet.
The topic is still in its infancy. Although the Internet makes it easy for those affected to access practical information, histamine intolerance is not yet listed as a disease in the WHO's ICD (International Statistical Classification of Diseases and Related Health Problems).
Although interest in histamine intolerance has increased considerably in recent years, yet more scientific knowledge is needed to define, diagnose and clinically treat this condition.
milVIVA wishes you success on your journey with many helpful discoveries. We would be delighted if you share your findings and feedback with us.